The FCER2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to FCER2. This antibody recognizes Human, Mouse, and Rat antigen. The FCER2 Antibody has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
Description: The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
Function: Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
Subunit Structure: Homotrimer.
Post-translational Modifications: N-and O-glycosylated. The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding